Originally Posted by Shadow
It sounds like the textures just aren't getting loaded for some reason. One thing you could try is open up your user.cfg file which is probably in C:\Users\YOUR USER NAME\AppData\Local\DroxOperative2\User and change the value for r_postponeTextureUpload to 0.
This didnt help, unfortunately. The game loaded for two seconds with the white box-red X's then closed itself. I didn't have a "user.cfg" file though, but I found that in "default.cfg"